Two complementary high-throughput kinetics (HTK) set-ups are available, i.e. a high-throughput kinetics screening set-up (HTK-S) and high-throughput kinetics mechanistic investigation set-up (HTK-MI). They are specifically designed to achieve the goals put forward in the information-driven catalyst design methodology, i.e. catalyst screening and mechanistic investigation while providing reliable intrinsic kinetic data for microkinetic model construction. The main goal of the HTK-S set-up is the fast parallel screening of a large variety and, hence, number of catalysts. Both simple and complex reaction networks can be dealt with. This set-up corresponds to the screening step. After the screening stage, a benchmark catalyst is selected, on which an extensive experimental study is performed on HTK-MI complemented by a few additional catalysts for the catalyst descriptor determination. This is depicted as the mechanistic investigation step.